Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM348655
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
IC50
6.40±n/a nM
Citation
 Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives US Patent  US9790230 Publication Date 10/17/2017 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM348655
Synonyms:
4-Ethoxy-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]benzamide | US9790230, Example 17
Type:
Small organic molecule
Emp. Form.:
C20H22N2O3
Mol. Mass.:
338.4003
SMILES:
CCOc1ccc(cc1)C(=O)Nc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2 |r|
Structure:
Search PDB for entries with ligand similarity: