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Target
N-acetyltransferase Eis
Ligand
BDBM349592
Substrate
n/a
Meas. Tech.
Eis inhibition assay
IC50
100.0±n/a nM
Citation
 Garneau-Tsodikova, S; Tsodikov, OV; Posey, JE Eis inhibitors US Patent  US10208000 Publication Date 2/19/2019 
Target
Name:
N-acetyltransferase Eis
Synonyms:
Aminoglycoside N-acetyltransferase | EIS_MYCTU | Enhanced intracellular survival protein | N-acetyltransferase Eis | Protein-lysine N-acetyltransferase | eis
Type:
PROTEIN
Mol. Mass.:
43803.37
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
ChEMBL_116995
Residue:
402
Sequence:
MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVGMALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSELRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
  
Inhibitor
Name:
BDBM349592
Synonyms:
US10208000, Compound 34
Type:
Small organic molecule
Emp. Form.:
C15H12ClN3O4S
Mol. Mass.:
365.791
SMILES:
CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1
Structure:
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