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Target
Androgen receptor
Ligand
BDBM354714
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
43.6±n/a nM
Citation
 Choi, SP; Choi, SM; Son, BH; Kim, HJ; Kim, JM; Jang, BJ; Sung, JH; Lee, JH; Kim, E; Kang, KK; Kim, S Oxazolidine-based compound and selective androgen receptor agonist comprising same US Patent  US9809583 Publication Date 11/7/2017 
Target
Name:
Androgen receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
97086.15
Organism:
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Description:
A0A0D9RHK8
Residue:
900
Sequence:
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLQQQQQQQQQQQQQQETSPRQQQKQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVPEPGAAVAAGKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSNGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPVLGVPPGVRPIPCAPLAECKGSLLDDSAGKSTEDTVEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGAGEAGAVAPYGYTRPPQGLAGQEGDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETAQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
  
Inhibitor
Name:
BDBM354714
Synonyms:
Preparation of ethyl(S)-3-((3-chloro-4-nitrophenyl)amino)-2-hydroxypropanoate | US9809583, Example 26
Type:
Small organic molecule
Emp. Form.:
C19H13ClF6N2OS
Mol. Mass.:
466.828
SMILES:
FC(F)(F)[C@H]1O[C@H](CSc2ccc(Cl)cc2)CN1c1ccc(C#N)c(c1)C(F)(F)F |r|
Structure:
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