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Target
D(1A) dopamine receptor
Ligand
BDBM364314
Substrate
n/a
Meas. Tech.
cAMP HTRF Assay
Ki
49.4±n/a nM
Citation
 Gray, DL; Davoren, JE; Dounay, AB; Efremov, IV; Mente, SR; Subramanyam, C Heteroaromatic compounds and their use as dopamine D1 ligands US Patent  US9856263 Publication Date 1/2/2018 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM364314
Synonyms:
US9856263, 34
Type:
Small organic molecule
Emp. Form.:
C19H15FN4O
Mol. Mass.:
334.347
SMILES:
Cc1ncnc(C)c1-c1ccc(Oc2nccn3cccc23)c(F)c1
Structure:
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