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Target
D(2) dopamine receptor
Ligand
BDBM50192239
Substrate
n/a
Meas. Tech.
3H]-Spiperone Binding Assay
Ki
240±n/a nM
Citation
 Cremonesi, S; Micheli, F; Semerano, T; Tarsi, L Dopamine D3 receptor antagonists US Patent  US10239870 Publication Date 3/26/2019 
Target
Name:
D(2) dopamine receptor
Synonyms:
D2(Short) | Dopamine D2 S receptor
Type:
n/a
Mol. Mass.:
47370.77
Organism:
Homo sapiens (Human)
Description:
P14416-2
Residue:
414
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50192239
Synonyms:
CHEMBL3922143 | US10239870, Example 48
Type:
Small organic molecule
Emp. Form.:
C22H26FN5OS
Mol. Mass.:
427.538
SMILES:
Cc1ncoc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(F)cc3)C2)n1C |r|
Structure:
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