Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM371969
Substrate
n/a
Meas. Tech.
3H]-Spiperone Binding Assay
Ki
295±n/a nM
Citation
 Cremonesi, S; Micheli, F; Semerano, T; Tarsi, L Dopamine D3 receptor antagonists US Patent  US10239870 Publication Date 3/26/2019 
Target
Name:
D(2) dopamine receptor
Synonyms:
D2(Short) | Dopamine D2 S receptor
Type:
n/a
Mol. Mass.:
47370.77
Organism:
Homo sapiens (Human)
Description:
P14416-2
Residue:
414
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM371969
Synonyms:
US10239870, Example 213
Type:
Small organic molecule
Emp. Form.:
C23H24F4N6S
Mol. Mass.:
492.535
SMILES:
Cn1c(SCCCN2CC[C@]3(CC3c3ccc(cc3F)C(F)(F)F)C2)nnc1-c1ccncn1 |r|
Structure:
Search PDB for entries with ligand similarity: