Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM259986
Substrate
n/a
Meas. Tech.
cAMP Assay
Temperature
310.15±n/a K
EC50
8.4±n/a nM
Comments
extracted
Citation
 Grether, U; Kimbara, A; Nettekoven, M; Ricklin, F; Roever, S; Rogers-Evans, M; Schulz-Gasch, T Pyrazol derivatives US Patent  US9694012 Publication Date 7/4/2017 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM259986
Synonyms:
US9512132, 22
Type:
Small organic molecule
Emp. Form.:
C20H22F2N6O
Mol. Mass.:
400.4251
SMILES:
CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(CC(=O)c3ccccn3)c2n1
Structure:
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