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Target
Protein Wnt-3a
Ligand
BDBM263573
Substrate
n/a
Meas. Tech.
WNT Pathway Reporter Gene Assay
IC50
<3.00±n/a nM
Citation
 An, S Compounds for treatment of fibrosis diseases US Patent  US10285988 Publication Date 5/14/2019 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A | WNT3A_HUMAN
Type:
PROTEIN
Mol. Mass.:
39379.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469237
Residue:
352
Sequence:
MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM263573
Synonyms:
N-(3-methyl-4-(2-methylpyridin-4-yl)benzyl)-6-(2-methylpyridin-4-yl)-2,7-naphthyridin-1-amine (Compound No. 2) | US10087181, Compound 2 | US10285988, Compound 2 | US9713612, 2
Type:
Small organic molecule
Emp. Form.:
C28H25N5
Mol. Mass.:
431.5316
SMILES:
Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(c(C)c3)-c3ccnc(C)c3)c2cn1
Structure:
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