Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37334
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
>45000±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37334
Synonyms:
4-[3-(3,5-dimethoxyphenyl)-4-keto-phthalazine-1-carbonyl]piperazine-1-carboxylic acid ethyl ester | 4-[[3-(3,5-dimethoxyphenyl)-4-oxo-1-phthalazinyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester | MLS000047572 | SMR000033583 | cid_3243642 | ethyl 4-[3-(3,5-dimethoxyphenyl)-4-oxidanylidene-phthalazin-1-yl]carbonylpiperazine-1-carboxylate | ethyl 4-[3-(3,5-dimethoxyphenyl)-4-oxophthalazine-1-carbonyl]piperazine-1-carboxylate | ethyl 4-{[3-(3,5-dimethoxyphenyl)-4-oxo-3,4-dihydrophthalazin-1-yl]carbonyl}piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C24H26N4O6
Mol. Mass.:
466.4864
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)c1nn(-c2cc(OC)cc(OC)c2)c(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: