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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37093
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37093
Synonyms:
1-[2-(2-bromophenoxy)propanoyl]indoline | 2-(2-bromanylphenoxy)-1-(2,3-dihydroindol-1-yl)propan-1-one | 2-(2-bromophenoxy)-1-(2,3-dihydroindol-1-yl)-1-propanone | 2-(2-bromophenoxy)-1-(2,3-dihydroindol-1-yl)propan-1-one | 2-(2-bromophenoxy)-1-indolin-1-yl-propan-1-one | MLS000090377 | SMR000024987 | cid_3244853
Type:
Small organic molecule
Emp. Form.:
C17H16BrNO2
Mol. Mass.:
346.218
SMILES:
CC(Oc1ccccc1Br)C(=O)N1CCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: