Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37449
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
6471±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37449
Synonyms:
2-[1-[(5-bromanylpyridin-2-yl)amino]ethyl]-4-chloranyl-phenol | 2-[1-[(5-bromo-2-pyridinyl)amino]ethyl]-4-chlorophenol | 2-[1-[(5-bromo-2-pyridyl)amino]ethyl]-4-chloro-phenol | 2-[1-[(5-bromopyridin-2-yl)amino]ethyl]-4-chlorophenol | 2-{1-[(5-bromo-2-pyridinyl)amino]ethyl}-4-chlorophenol | MLS000096900 | SMR000074649 | cid_2947289
Type:
Small organic molecule
Emp. Form.:
C13H12BrClN2O
Mol. Mass.:
327.604
SMILES:
CC(Nc1ccc(Br)cn1)c1cc(Cl)ccc1O
Structure:
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