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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35356
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35356
Synonyms:
MLS000071837 | N-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2-[1-(2,4-dimethoxy-phenyl)-1H-tetrazol-5-ylsulfanyl]-acetamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[1-(2,4-dimethoxyphenyl)tetrazol-5-yl]sulfanylacetamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(2,4-dimethoxyphenyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]ethanamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(2,4-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(2,4-dimethoxyphenyl)tetrazol-5-yl]thio]acetamide | SMR000003515 | cid_647361
Type:
Small organic molecule
Emp. Form.:
C19H19N5O5S
Mol. Mass.:
429.45
SMILES:
COc1ccc(c(OC)c1)-n1nnnc1SCC(=O)Nc1ccc2OCCOc2c1
Structure:
Search PDB for entries with ligand similarity: