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Target
Mevalonate kinase
Ligand
BDBM37958
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM37958
Synonyms:
6-Amino-4-(4-carbamoylmethoxy-2-chloro-5-methoxy-phenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylic acid methyl ester | 6-amino-4-[4-(2-amino-2-keto-ethoxy)-2-chloro-5-methoxy-phenyl]-5-cyano-2-methyl-4H-pyran-3-carboxylic acid methyl ester | 6-amino-4-[4-(2-amino-2-oxoethoxy)-2-chloro-5-methoxyphenyl]-5-cyano-2-methyl-4H-pyran-3-carboxylic acid methyl ester | MLS000073401 | SMR000015000 | cid_646731 | methyl 6-amino-4-[4-(2-amino-2-oxoethoxy)-2-chloro-5-methoxyphenyl]-5-cyano-2-methyl-4H-pyran-3-carboxylate | methyl 6-azanyl-4-[4-(2-azanyl-2-oxidanylidene-ethoxy)-2-chloranyl-5-methoxy-phenyl]-5-cyano-2-methyl-4H-pyran-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H18ClN3O6
Mol. Mass.:
407.805
SMILES:
COC(=O)C1=C(C)OC(=N)C(C#N)C1c1cc(OC)c(OCC(N)=O)cc1Cl |c:4|
Structure:
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