Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM38903
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
IC50
3210±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM38903
Synonyms:
6-(4-ethylphenyl)-2,3-dimethyl-imidazo[1,2-b][1,2,4]triazine | 6-(4-ethylphenyl)-2,3-dimethylimidazo[1,2-b][1,2,4]triazine | MLS000036814 | SMR000035409 | cid_661897
Type:
Small organic molecule
Emp. Form.:
C15H16N4
Mol. Mass.:
252.3143
SMILES:
CCc1ccc(cc1)-c1cn2nc(C)c(C)nc2n1
Structure:
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