Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM35386
Substrate
n/a
Meas. Tech.
MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment: Cdc25B Dose Response Selectivity Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment: Cdc25B Dose Response Selectivity Assay PubChem Bioassay (2007)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM35386
Synonyms:
MLS000095236 | N-(4-ethylphenyl)-2-[3-(2-morpholin-4-ylethyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-ethanamide | N-(4-ethylphenyl)-2-[3-(2-morpholin-4-ylethyl)-4-oxoquinazolin-2-yl]sulfanylacetamide | N-(4-ethylphenyl)-2-[[3-[2-(4-morpholinyl)ethyl]-4-oxo-2-quinazolinyl]thio]acetamide | N-(4-ethylphenyl)-2-[[4-keto-3-(2-morpholinoethyl)quinazolin-2-yl]thio]acetamide | N-(4-ethylphenyl)-2-{[3-(2-morpholin-4-ylethyl)-4-oxo-3,4-dihydroquinazolin-2-yl]thio}acetamide | SMR000030790 | cid_3237221
Type:
Small organic molecule
Emp. Form.:
C24H28N4O3S
Mol. Mass.:
452.569
SMILES:
CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCN2CCOCC2)cc1
Structure:
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