Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM40450
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Ki
>44300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM40450
Synonyms:
N-(2,6-dimethylphenyl)-2-[(1-oxo-2-thiophen-2-ylethyl)amino]-2-phenylacetamide | N-(2,6-dimethylphenyl)-2-phenyl-2-(2-thiophen-2-ylethanoylamino)ethanamide | N-(2,6-dimethylphenyl)-2-phenyl-2-[(2-thiophen-2-ylacetyl)amino]acetamide | N-(2,6-dimethylphenyl)-2-phenyl-2-[[2-(2-thienyl)acetyl]amino]acetamide | UNM000003608101 | cid_4656066
Type:
Small organic molecule
Emp. Form.:
C22H22N2O2S
Mol. Mass.:
378.487
SMILES:
Cc1cccc(C)c1NC(=O)C(NC(=O)Cc1cccs1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: