Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31001
Substrate
n/a
Meas. Tech.
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists
EC50
>40000±n/a nM
Citation
 PubChem, PC S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31001
Synonyms:
(4-Amino-furazan-3-yl)-(4-methyl-piperazin-1-yl)-methanone oxime | (4E)-4-[(4-methyl-1-piperazinyl)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine | (4E)-4-[(4-methylpiperazin-1-yl)-nitroso-methylidene]-1,2,5-oxadiazol-3-amine | (4E)-4-[(4-methylpiperazin-1-yl)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine | MLS000070315 | SMR000001272 | [(4E)-4-[(4-methylpiperazino)-nitroso-methylene]furazan-3-yl]amine | cid_6364821
Type:
Small organic molecule
Emp. Form.:
C8H14N6O2
Mol. Mass.:
226.2358
SMILES:
CN1CCN(CC1)C(N=O)c1nonc1N
Structure:
Search PDB for entries with ligand similarity: