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Target
Cathepsin S
Ligand
BDBM41167
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
16855.2±682.032 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41167
Synonyms:
4,6-bis(4-morpholinyl)-1,3,5-triazine-2-carbonitrile | 4,6-dimorpholin-4-yl-1,3,5-triazine-2-carbonitrile | 4,6-dimorpholino-s-triazine-2-carbonitrile | MLS000085814 | SMR000020943 | cid_755373
Type:
Small organic molecule
Emp. Form.:
C12H16N6O2
Mol. Mass.:
276.2944
SMILES:
N#Cc1nc(nc(n1)N1CCOCC1)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: