Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41358
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41358
Synonyms:
MLS000117528 | SMR000094476 | [5-(brosylmethyl)-2-furyl]-morpholino-methanone | [5-[(4-bromophenyl)sulfonylmethyl]-2-furanyl]-(4-morpholinyl)methanone | [5-[(4-bromophenyl)sulfonylmethyl]furan-2-yl]-morpholin-4-yl-methanone | [5-[(4-bromophenyl)sulfonylmethyl]furan-2-yl]-morpholin-4-ylmethanone | cid_5307553
Type:
Small organic molecule
Emp. Form.:
C16H16BrNO5S
Mol. Mass.:
414.271
SMILES:
Brc1ccc(cc1)S(=O)(=O)Cc1ccc(o1)C(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: