Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM35491
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
20817.8±5400.82 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM35491
Synonyms:
Benzoic acid 5-amino-1-(4-methoxy-benzenesulfonyl)-1H-pyrazol-3-yl ester | MLS000033898 | SMR000014915 | [5-amino-1-(4-methoxyphenyl)sulfonylpyrazol-3-yl] benzoate | [5-azanyl-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] benzoate | benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester | benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-pyrazol-3-yl] ester | cid_655490
Type:
Small organic molecule
Emp. Form.:
C17H15N3O5S
Mol. Mass.:
373.383
SMILES:
COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccccc2)cc1N
Structure:
Search PDB for entries with ligand similarity: