Reaction Details Report a problem with these data
Target
Cathepsin G
Ligand
BDBM37413
Substrate
n/a
Meas. Tech.
Cathepsin G dose-response confirmation
IC50
1392.29±90.8785 nM
Citation
 PubChem, PC Cathepsin G dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM37413
Synonyms:
7-methoxy-N-(3-pyridinylmethyl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | 7-methoxy-N-(3-pyridylmethyl)-4,5-dihydrobenz[g]indoxazene-3-carboxamide | 7-methoxy-N-(pyridin-3-ylmethyl)-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide | 7-methoxy-N-(pyridin-3-ylmethyl)-4,5-dihydronaphtho[2,1-d]isoxazole-3-carboxamide | MLS000087435 | SMR000023658 | cid_3241578
Type:
Small organic molecule
Emp. Form.:
C19H17N3O3
Mol. Mass.:
335.3566
SMILES:
COc1ccc2-c3onc(C(=O)NCc4cccnc4)c3CCc2c1
Structure:
Search PDB for entries with ligand similarity: