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Target
Galanin receptor type 2
Ligand
BDBM42049
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
45640±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42049
Synonyms:
4-(8-Fluoro-5H-pyrimido[5,4-b]indol-4-yl)-piperazine-1-carboxylic acid ethyl ester | 4-(8-fluoro-5H-pyrimid[5,4-b]indol-4-yl)piperazine-1-carboxylic acid ethyl ester | 4-(8-fluoro-5H-pyrimido[5,4-b]indol-4-yl)-1-piperazinecarboxylic acid ethyl ester | MLS000555912 | SMR000147429 | cid_919665 | ethyl 4-(8-fluoranyl-5H-pyrimido[5,4-b]indol-4-yl)piperazine-1-carboxylate | ethyl 4-(8-fluoro-5H-pyrimido[5,4-b]indol-4-yl)piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H18FN5O2
Mol. Mass.:
343.3555
SMILES:
CCOC(=O)N1CCN(CC1)c1ncnc2c3cc(F)ccc3[nH]c12
Structure:
Search PDB for entries with ligand similarity: