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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM39592
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM39592
Synonyms:
MLS000078483 | N-(2-furanylmethyl)-2-(6-methoxy-2-methyl-4-oxo-1-quinolinyl)acetamide | N-(2-furfuryl)-2-(4-keto-6-methoxy-2-methyl-1-quinolyl)acetamide | N-(furan-2-ylmethyl)-2-(6-methoxy-2-methyl-4-oxidanylidene-quinolin-1-yl)ethanamide | N-(furan-2-ylmethyl)-2-(6-methoxy-2-methyl-4-oxoquinolin-1-yl)acetamide | SMR000042295 | cid_661771
Type:
Small organic molecule
Emp. Form.:
C18H18N2O4
Mol. Mass.:
326.3465
SMILES:
COc1ccc2n(CC(=O)NCc3ccco3)c(C)cc(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: