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Target
Neuropeptide Y receptor type 1
Ligand
BDBM42413
Substrate
n/a
Meas. Tech.
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42413
Synonyms:
(4E)-3-hydroxy-4-[4-(4-methoxyphenoxy)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,5-dienone | (4E)-3-hydroxy-4-[4-(4-methoxyphenoxy)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,5-dien-1-one | (4E)-3-hydroxy-4-[4-(4-methoxyphenoxy)-3-pyrazolin-3-ylidene]cyclohexa-2,5-dien-1-one | (4E)-4-[4-(4-methoxyphenoxy)-1,2-dihydropyrazol-3-ylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one | MLS000083068 | SMR000045511 | cid_5389842
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4
Mol. Mass.:
298.2934
SMILES:
COc1ccc(Oc2c[nH]nc2-c2ccc(O)cc2O)cc1
Structure:
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