Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM39426
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM39426
Synonyms:
7-amino-3-phenyl-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester | 7-amino-3-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester | MLS000075211 | SMR000014414 | cid_649053 | ethyl 7-amino-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate | ethyl 7-azanyl-3-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H14N4O2
Mol. Mass.:
282.2973
SMILES:
CCOC(=O)c1cnc2c(cnn2c1N)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: