Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43665
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43665
Synonyms:
3-(2-amino-1,3-thiazol-5-yl)chromen-2-one | 3-(2-amino-5-thiazolyl)-1-benzopyran-2-one | 3-(2-aminothiazol-5-yl)coumarin | 3-(2-azanyl-1,3-thiazol-5-yl)chromen-2-one | MLS000038134 | SMR000034096 | cid_666986
Type:
Small organic molecule
Emp. Form.:
C12H8N2O2S
Mol. Mass.:
244.269
SMILES:
Nc1ncc(s1)-c1cc2ccccc2oc1=O
Structure:
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