Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43666
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43666
Synonyms:
(2-phenyl-1,3-thiazol-4-yl)methyl thiophene-2-carboxylate | 2-thiophenecarboxylic acid (2-phenyl-4-thiazolyl)methyl ester | MLS000054931 | SMR000066875 | cid_2115030 | thiophene-2-carboxylic acid (2-phenylthiazol-4-yl)methyl ester
Type:
Small organic molecule
Emp. Form.:
C15H11NO2S2
Mol. Mass.:
301.383
SMILES:
O=C(OCc1csc(n1)-c1ccccc1)c1cccs1
Structure:
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