Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM41395
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM41395
Synonyms:
MLS000093387 | N-(6-methoxy-4-pyrimidinyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | N-(6-methoxypyrimidin-4-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide | N-(6-methoxypyrimidin-4-yl)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide | SMR000029005 | cid_3237573
Type:
Small organic molecule
Emp. Form.:
C14H15N3O2S
Mol. Mass.:
289.353
SMILES:
COc1cc(NC(=O)c2csc3CCCCc23)ncn1
Structure:
Search PDB for entries with ligand similarity: