Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43667
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43667
Synonyms:
5-(4-bromophenyl)-N-prop-2-enyl-1,2-oxazole-3-carboxamide | 5-(4-bromophenyl)-N-prop-2-enyl-3-isoxazolecarboxamide | MLS000087031 | N-allyl-5-(4-bromophenyl)isoxazole-3-carboxamide | SMR000023254 | cid_3238993
Type:
Small organic molecule
Emp. Form.:
C13H11BrN2O2
Mol. Mass.:
307.143
SMILES:
Brc1ccc(cc1)-c1cc(no1)C(=O)NCC=C
Structure:
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