Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43668
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43668
Synonyms:
1,3-benzodioxol-5-yl-(6-methoxy-1,3-benzothiazol-2-yl)amine | MLS000045469 | N-(1,3-benzodioxol-5-yl)-6-methoxy-1,3-benzothiazol-2-amine | N-1,3-benzodioxol-5-yl-6-methoxy-1,3-benzothiazol-2-amine | SMR000027226 | cid_3239232
Type:
Small organic molecule
Emp. Form.:
C15H12N2O3S
Mol. Mass.:
300.332
SMILES:
COc1ccc2nc(Nc3ccc4OCOc4c3)sc2c1
Structure:
Search PDB for entries with ligand similarity: