Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43669
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43669
Synonyms:
5-(4-methoxyphenyl)-N-sec-butyl-isoxazole-3-carboxamide | MLS000087047 | N-(sec-butyl)-5-(4-methoxyphenyl)isoxazole-3-carboxamide | N-butan-2-yl-5-(4-methoxyphenyl)-1,2-oxazole-3-carboxamide | N-butan-2-yl-5-(4-methoxyphenyl)-3-isoxazolecarboxamide | SMR000023270 | cid_3240005
Type:
Small organic molecule
Emp. Form.:
C15H18N2O3
Mol. Mass.:
274.315
SMILES:
CCC(C)NC(=O)c1cc(on1)-c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: