Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM38116
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM38116
Synonyms:
MLS000087665 | N-(7-methyl-2-thiazolo[4,5-g][1,3]benzothiazolyl)-2-furancarboxamide | N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)furan-2-carboxamide | N-(7-methyl[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)-2-furamide | N-(7-methylthiazolo[4,5-g][1,3]benzothiazol-2-yl)-2-furamide | SMR000023886 | cid_3240171
Type:
Small organic molecule
Emp. Form.:
C14H9N3O2S2
Mol. Mass.:
315.37
SMILES:
Cc1nc2ccc3nc(NC(=O)c4ccco4)sc3c2s1
Structure:
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