Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43671
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43671
Synonyms:
4-(6-ethoxy-4-methyl-2-quinazolinyl)morpholine | 4-(6-ethoxy-4-methyl-quinazolin-2-yl)morpholine | 4-(6-ethoxy-4-methylquinazolin-2-yl)morpholine | 6-ethoxy-4-methyl-2-(4-morpholinyl)quinazoline | MLS000066575 | SMR000082419 | cid_1257512
Type:
Small organic molecule
Emp. Form.:
C15H19N3O2
Mol. Mass.:
273.3303
SMILES:
CCOc1ccc2nc(nc(C)c2c1)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: