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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43675
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43675
Synonyms:
6-[(5-chloranyl-1,3-benzoxazol-2-yl)sulfanylmethyl]-N2,N2-dimethyl-1,3,5-triazine-2,4-diamine | 6-[(5-chloro-1,3-benzoxazol-2-yl)sulfanylmethyl]-2-N,2-N-dimethyl-1,3,5-triazine-2,4-diamine | 6-[[(5-chloro-1,3-benzoxazol-2-yl)thio]methyl]-N2,N2-dimethyl-1,3,5-triazine-2,4-diamine | 6-{[(5-chloro-1,3-benzoxazol-2-yl)thio]methyl}-N,N-dimethyl-1,3,5-triazine-2,4-diamine | MLS000099949 | SMR000081132 | [4-amino-6-[[(5-chloro-1,3-benzoxazol-2-yl)thio]methyl]-s-triazin-2-yl]-dimethyl-amine | cid_847858
Type:
Small organic molecule
Emp. Form.:
C13H13ClN6OS
Mol. Mass.:
336.8
SMILES:
CN(C)c1nc(N)nc(CSc2nc3cc(Cl)ccc3o2)n1
Structure:
Search PDB for entries with ligand similarity: