Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM42845
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM42845
Synonyms:
MLS000102787 | N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-2-furamide | N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-furancarboxamide | N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]furan-2-carboxamide | SMR000016908 | cid_4336986
Type:
Small organic molecule
Emp. Form.:
C17H11N3O2S
Mol. Mass.:
321.353
SMILES:
O=C(Nc1ccc(cc1)-c1nc2cccnc2s1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: