Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43680
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43680
Synonyms:
MLS000110502 | SMR000106431 | cid_883228 | phenyl-(4-pyrrolidin-1-ylphenyl)methanone | phenyl-(4-pyrrolidinophenyl)methanone | phenyl-[4-(1-pyrrolidinyl)phenyl]methanone
Type:
Small organic molecule
Emp. Form.:
C17H17NO
Mol. Mass.:
251.323
SMILES:
O=C(c1ccccc1)c1ccc(cc1)N1CCCC1
Structure:
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