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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM46083
Substrate
n/a
Meas. Tech.
SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay
IC50
73800±n/a nM
Citation
 PubChem, PC SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM46083
Synonyms:
(3Z)-1-butyl-3-[[2-(trifluoromethyl)phenyl]hydrazinylidene]-2-indolone | (3Z)-1-butyl-3-[[2-(trifluoromethyl)phenyl]hydrazinylidene]indol-2-one | (3Z)-1-butyl-3-[[2-(trifluoromethyl)phenyl]hydrazono]oxindole | MLS-0390914.0001 | cid_25181230
Type:
Small organic molecule
Emp. Form.:
C19H18F3N3O
Mol. Mass.:
361.3609
SMILES:
CCCCN1C(=O)C(=NNc2ccccc2C(F)(F)F)c2ccccc12 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: