Reaction Details Report a problem with these data
Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32278
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
7820±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32278
Synonyms:
(6-anilino-2-pyridyl)-phenyl-amine | 2-N,6-N-diphenylpyridine-2,6-diamine | MLS000534997 | N,N'-diphenyl-2,6-pyridinediamine | N2,N6-diphenylpyridine-2,6-diamine | SMR000142433 | cid_1311254
Type:
Small organic molecule
Emp. Form.:
C17H15N3
Mol. Mass.:
261.3211
SMILES:
N(c1ccccc1)c1cccc(Nc2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: