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Target
Bcl-2-like protein 2
Ligand
BDBM46312
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
9000±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM46312
Synonyms:
4-(3-isopropoxypropylamino)-6,7-dimethoxy-1H-quinazoline-2-thione | 6,7-dimethoxy-4-(3-propan-2-yloxypropylamino)-1H-quinazoline-2-thione | MLS000520260 | SMR000130673 | cid_9551010
Type:
Small organic molecule
Emp. Form.:
C16H23N3O3S
Mol. Mass.:
337.437
SMILES:
COc1cc2nc(=S)[nH]c(NCCCOC(C)C)c2cc1OC
Structure:
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