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Target
Bcl-2-like protein 2
Ligand
BDBM32279
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
2670±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32279
Synonyms:
4-(4-carbethoxyanilino)quinazoline-2-carboxylic acid ethyl ester | 4-(4-ethoxycarbonylanilino)-2-quinazolinecarboxylic acid ethyl ester | MLS000519322 | SMR000129741 | cid_1192535 | ethyl 4-(4-ethoxycarbonylanilino)quinazoline-2-carboxylate | ethyl 4-[(4-ethoxycarbonylphenyl)amino]quinazoline-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H19N3O4
Mol. Mass.:
365.3826
SMILES:
CCOC(=O)c1ccc(Nc2nc(nc3ccccc23)C(=O)OCC)cc1
Structure:
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