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Target
Regulator of G-protein signaling 8
Ligand
BDBM47801
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47801
Synonyms:
4-methoxy-N-(4-pyrrol-1-ylphenyl)benzenesulfonamide | 4-methoxy-N-[4-(1-pyrrolyl)phenyl]benzenesulfonamide | 4-methoxy-N-[4-(1H-pyrrol-1-yl)phenyl]benzenesulfonamide | MLS000736335 | SMR000338285 | cid_2768241
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3S
Mol. Mass.:
328.386
SMILES:
COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-n1cccc1
Structure:
Search PDB for entries with ligand similarity: