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Target
Regulator of G-protein signaling 8
Ligand
BDBM47826
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47826
Synonyms:
MLS000767196 | N-[2-(5-Ethanesulfonyl-3-nitro-thiophen-2-ylsulfanyl)-phenyl]-acetamide | N-[2-(5-ethylsulfonyl-3-nitro-thiophen-2-yl)sulfanylphenyl]ethanamide | N-[2-(5-ethylsulfonyl-3-nitrothiophen-2-yl)sulfanylphenyl]acetamide | N-[2-[(5-esyl-3-nitro-2-thienyl)thio]phenyl]acetamide | N-[2-[(5-ethylsulfonyl-3-nitro-2-thiophenyl)thio]phenyl]acetamide | SMR000429517 | cid_1583996
Type:
Small organic molecule
Emp. Form.:
C14H14N2O5S3
Mol. Mass.:
386.466
SMILES:
CCS(=O)(=O)c1cc(c(Sc2ccccc2NC(C)=O)s1)[N+]([O-])=O
Structure:
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