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Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51320
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51320
Synonyms:
4-[2-(4-methylphenyl)-3,4-dioxo-1-cyclobutenyl]-1-piperazinecarboxylic acid ethyl ester | 4-[3,4-diketo-2-(p-tolyl)cyclobuten-1-yl]piperazine-1-carboxylic acid ethyl ester | MLS000094571 | SMR000030122 | cid_3236271 | ethyl 4-[2-(4-methylphenyl)-3,4-bis(oxidanylidene)cyclobuten-1-yl]piperazine-1-carboxylate | ethyl 4-[2-(4-methylphenyl)-3,4-dioxocyclobut-1-en-1-yl]piperazine-1-carboxylate | ethyl 4-[2-(4-methylphenyl)-3,4-dioxocyclobuten-1-yl]piperazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H20N2O4
Mol. Mass.:
328.3624
SMILES:
CCOC(=O)N1CCN(CC1)c1c(-c2ccc(C)cc2)c(=O)c1=O
Structure:
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