Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52261
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
39414±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52261
Synonyms:
(4Z)-2-[(E)-2-(3-nitrophenyl)ethenyl]-4-(phenylazanylmethylidene)-1,3-oxazol-5-one | (4Z)-4-(anilinomethylene)-2-[(E)-2-(3-nitrophenyl)vinyl]-2-oxazolin-5-one | (4Z)-4-(anilinomethylidene)-2-[(E)-2-(3-nitrophenyl)ethenyl]-1,3-oxazol-5-one | (4Z)-4-(anilinomethylidene)-2-[(E)-2-(3-nitrophenyl)ethenyl]-5-oxazolone | MLS000521377 | SMR000131785 | cid_6935000
Type:
Small organic molecule
Emp. Form.:
C18H13N3O4
Mol. Mass.:
335.3135
SMILES:
Oc1oc(\C=C\c2cccc(c2)[N+]([O-])=O)nc1\C=N\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: