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Target
Zinc finger protein mex-5
Ligand
BDBM53290
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
8174±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM53290
Synonyms:
2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid | 2-[4-[(4-bromophenyl)sulfonylamino]-1-oxidanyl-naphthalen-2-yl]sulfanylethanoic acid | 2-[[4-(brosylamino)-1-hydroxy-2-naphthyl]thio]acetic acid | 2-[[4-[(4-bromophenyl)sulfonylamino]-1-hydroxy-2-naphthalenyl]thio]acetic acid | MLS001196198 | SMR000558497 | [(4-{[(4-bromophenyl)sulfonyl]amino}-1-hydroxy-2-naphthyl)thio]acetic acid | cid_992586
Type:
Small organic molecule
Emp. Form.:
C18H14BrNO5S2
Mol. Mass.:
468.341
SMILES:
OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O
Structure:
Search PDB for entries with ligand similarity: