Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM53399
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
50036±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM53399
Synonyms:
(6E)-6-[[(6-chloro-1,2-dihydropyridazin-3-yl)hydrazo]methylidene]cyclohex-4-ene-1,2,3-trione | (6E)-6-[[2-(6-chloranyl-1,2-dihydropyridazin-3-yl)hydrazinyl]methylidene]cyclohex-4-ene-1,2,3-trione | (6E)-6-[[2-(6-chloro-1,2-dihydropyridazin-3-yl)hydrazinyl]methylidene]cyclohex-4-ene-1,2,3-trione | (6E)-6-[[N'-(6-chloro-1,2-dihydropyridazin-3-yl)hydrazino]methylene]cyclohex-4-ene-1,2,3-trione | MLS001171031 | SMR000588539 | cid_5831921
Type:
Small organic molecule
Emp. Form.:
C11H9ClN4O3
Mol. Mass.:
280.667
SMILES:
Oc1ccc(CN=Nc2ccc(Cl)nn2)c(O)c1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: