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Target
POsterior Segregation
Ligand
BDBM53393
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
71231±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM53393
Synonyms:
3,4,5-trihydroxy-N'-{(1E)-[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methylene}benzohydrazide | 5-hydroxy-N'-[(Z)-(3-hydroxy-2-methyl-5-methylol-1H-pyridin-4-ylidene)methyl]-3,4-diketo-cyclohexa-1,5-diene-1-carbohydrazide | 5-hydroxy-N'-[(Z)-[3-hydroxy-5-(hydroxymethyl)-2-methyl-1H-pyridin-4-ylidene]methyl]-3,4-dioxo-1-cyclohexa-1,5-dienecarbohydrazide | 5-hydroxy-N'-[(Z)-[3-hydroxy-5-(hydroxymethyl)-2-methyl-1H-pyridin-4-ylidene]methyl]-3,4-dioxocyclohexa-1,5-diene-1-carbohydrazide | MLS000673322 | N'-[(Z)-[5-(hydroxymethyl)-2-methyl-3-oxidanyl-1H-pyridin-4-ylidene]methyl]-5-oxidanyl-3,4-bis(oxidanylidene)cyclohexa-1,5-diene-1-carbohydrazide | SMR000314563 | cid_6251022
Type:
Small organic molecule
Emp. Form.:
C15H15N3O6
Mol. Mass.:
333.2961
SMILES:
Cc1ncc(CO)c(CNNC(=O)C2=CC(=O)C(=O)C(=O)C2)c1O |t:13|
Structure:
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