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Target
Dual specificity protein phosphatase 6
Ligand
BDBM46207
Substrate
n/a
Meas. Tech.
MKP-3 in vitro HTS assay
IC50
76700±n/a nM
Citation
 PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM46207
Synonyms:
4-[[5-(4-bromophenyl)-2-furoyl]thiocarbamoylamino]benzoic acid | 4-[[5-(4-bromophenyl)furan-2-carbonyl]carbamothioylamino]benzoic acid | 4-[[5-(4-bromophenyl)furan-2-yl]carbonylcarbamothioylamino]benzoic acid | 4-[[[[[5-(4-bromophenyl)-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acid | MLS-0383777.0001 | cid_1328767
Type:
Small organic molecule
Emp. Form.:
C19H13BrN2O4S
Mol. Mass.:
445.287
SMILES:
OC(=O)c1ccc(NC(=S)NC(=O)c2ccc(o2)-c2ccc(Br)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: