Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM55514
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
50000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM55514
Synonyms:
(2-oxidanylidene-1,2-diphenyl-ethyl) 3-acetamido-4-methyl-benzoate | (2-oxo-1,2-diphenylethyl) 3-acetamido-4-methylbenzoate | 2-oxo-1,2-diphenylethyl 3-(acetylamino)-4-methylbenzoate | 3-acetamido-4-methyl-benzoic acid desyl ester | 3-acetamido-4-methylbenzoic acid (2-oxo-1,2-diphenylethyl) ester | MLS000576324 | SMR000197964 | cid_2934084
Type:
Small organic molecule
Emp. Form.:
C24H21NO4
Mol. Mass.:
387.4278
SMILES:
CC(=O)Nc1cc(ccc1C)C(=O)OC(C(=O)c1ccccc1)c1ccccc1
Structure:
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