Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM44422
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
50000±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM44422
Synonyms:
3-benzyl-6,6-dimethyl-5,7-dihydro-1H-indazol-4-one | 6,6-dimethyl-3-(phenylmethyl)-5,7-dihydro-1H-indazol-4-one | MLS000113801 | SMR000109693 | cid_705460
Type:
Small organic molecule
Emp. Form.:
C16H18N2O
Mol. Mass.:
254.3269
SMILES:
CC1(C)Cc2n[nH]c(Cc3ccccc3)c2C(=O)C1
Structure:
Search PDB for entries with ligand similarity: